Placeholder: Epigenetic orthodontics means that various human genes or combinations of the patient’s naturally-inherited genes from parents are harnessed in combination or independently with various orthodontic, orthopedic and/or pneumopedic devices like DNA appliances or AGGA appliance to modify, change or attenuate the physical location of natural teeth, jaws and airway in 3-D space during orthodontic, orthopedic and/or pneumopedic treatments, based on the concept of ‘temporo-spatial patterning.’ The term “temporo-spatial patterning” like Global Positioning Satellite (GPS) implies that the spatial organization of the teeth, jaws and airway can be mapped in 3-D space at known anatomical locations using x, y, z coordinates. The pattern in 3-D space of craniofacial structures are encoded within the patient’s genome. Biomimetic, functional appliance are capable of modulating genetic pathways, which are effectively dormant or inactive, and are capable of restarting craniofacial development in adult patients as well as in children. In addition, abnormal patterning is corrected, in part, through the deployment of orthodontic, orthopedic and/or pneumopedic devices which may evoke natural developmental processes that improve a patient’s airway and thereby ameliorate or prevent airway issues such as snoring and other forms of sleep-disordered breathing through non-surgical airway remodeling.